C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/64 (2006.01) A61K 31/496 (2006.01) A61P 9/00 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2550257
Disclosed are novel substituted heterocyclic derivatives having the structure of Formula (I): The compounds are useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, diabetes, and myocardial infarction.
L'invention porte sur de nouveaux dérivés hétérocycliques substitués possédant la structure de la formule (1). Les composés de l'invention sont utilisés dans le traitement de divers états pathologiques, en particulier les maladies cardiovasculaires telles que l'arythmie atriale et ventriculaire, la claudication intermittente, l'angine de poitrine inversée, l'angor stable et instable, l'angor d'effort, l'insuffisance cardiaque globale, le diabète, et l'infarctus du myocarde.
Elzein Elfatih
Ibrahim Prabha
Palle Venkata
Rehder Kenneth
Zablocki Jeff
Cv Therapeutics Inc.
Smart & Biggar
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