1-alkoxy 1h-imidazo ring systems and methods

Details 1-alkoxy 1h-imidazo ring systems and methods 1-alkoxy 1h-imidazo ring systems and methods

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) C07D 471/14 (2006.01)

Patent

CA 2578741

Imidazo-containing compounds (e.g., imidazonaphthyridines, imidazopyridines, imidazoquinolines, and imidazotetrahydroquinolines) with an alkoxy substituent at the 1-position, pharmaceutical compositions containing the compounds and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

L'invention concerne des composés contenant imidazo (par exemple imidazonaphthyridines, imidazopyridines, imidazoquinoléines, et imidazotétrahydroquinoléines) avec un substituant alcoxy en position 1, des compositions pharmaceutiques contenant ces composés et des procédés d'utilisation de ces composés comme immunomodulateurs, afin d'induire une biosynthèse de cytokine chez des animaux et pour traiter des maladies, notamment des maladies virales et néoplastiques.

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