1-alkyl-2-(phenoxymethyl)-5-nitroimidazoles and process for...

C - Chemistry – Metallurgy – 07 – D

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260/315.25

C07D 233/94 (2006.01) C07D 233/54 (2006.01)

Patent

CA 1064506

ABSTRACT Novel 1-alkyl-2-(phenoxymethyl)-5-nitro-imidazoles of the formula Image wherein R1 is methyl or ethyl, R2 is trifluoromethyl, trichloro- methyl, nitro, cyano, methylsulfonyl or ethylsulfonyl, and R3 is hydrogen, fluorine, chlorine, bromine, iodine, trifluoro- methyl, trichloromethyl, cyano or nitro, and R4 is hydrogen or methyl, are described as well as a process for their manufacture. The novel compounds are active against trichomonads and amoebae and are especially suitable for the treatment of Fluor genitalis.

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