1-alkyl-3-thio-substituted indole-2-alkynoic acids useful...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/30 (2006.01) A61K 31/405 (2006.01) A61P 25/28 (2006.01) C07D 209/36 (2006.01) C07D 403/06 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2549119

Compounds of formula (I): modulate the activity of .UPSILON. -secretase, and hence find use in treatment or prevention of Alzheimer's disease and related conditions.

L'invention porte sur des composés de la formule 1 qui modulent l'activité de la Y-secrétase et qui sont par conséquent utilisés pour traiter ou prévenir la maladie d'Alzheimer et les états associés.

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