1-alkyl-androsta-1, 4-diene-3, 17-diones and their...

C - Chemistry – Metallurgy – 07 – J

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260/38

C07J 1/00 (2006.01)

Patent

CA 1223251

ABSTRACT Novel 1-alkyl-androsta-1,4-diene-3,17-diones and their manufacture and use Novel 1-alkyl-androsta-1,4-diene-3,17-diones of the general formula I Image (I) [in which R1 represents methyl, ethyl, hydroxymethyl, (C1-C3-alkoy)-methyl or (C1-C4-alkanoyloxy)-methyl, R6 represents H or methyl and R7 represents H or 7.alpha.- or 7.beta.-methyl] and processes for their manufacture. The novel compounds have an aromatase-inhibiting action and are suitable for fertility control and for the treatment of disorders caused by oestrogens; they may accordingly be made up with suitable carriers into pharmaceutical preparations.

456730

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