1-allyl ergot alkaloid derivatives, methods for their...

C - Chemistry – Metallurgy – 07 – D

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C07D 457/12 (2006.01) A61K 31/48 (2006.01) A61P 7/02 (2006.01) A61P 25/00 (2006.01) A61P 25/06 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2478393

This invention relates to 1-allyl ergot alkaloids and their derivatives with selective antagonistic properties to 5-HT2 receptors for the prevention of, and relief from, migraine-related headache, Parkinson's disease, disorders of the thrombocyte function, etc.

L'invention concerne des 1-allyl-alcaloïdes ergot et leurs dérivés présentant des propriétés antagonistes sélectives vis-à-vis des récepteurs 5-HT2, et destinés à prévenir et soulager, entre autres, des céphalées migraineuses, la maladie de Parkinson ainsi que des troubles de la fonction thrombocytaire.

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