1-amino-5-halogenouracils, process for their preparation,...

C - Chemistry – Metallurgy – 07 – D

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C07D 239/553 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2034224

ABSTRACT OF THE DISCLOSURE Disclosed are a central nervous system depressant which comprises a 1-amino-5-halogenouracil represented by the formula Image [I] wherein X represents a halogen atom, or a pharmaceutically acceptable salt thereof as an active ingredient; a 1-amino-5-halogenouracil represented by the formula Image [II] wherein X' represents chlorine, bromine or iodine, or a salt thereof; and a process for preparing a 1-amino-5-halogenouracil represented by the above shown formula [I] from a pyrimidine derivative represented by the formula Image [III] wherein X represents a halogen atom and R represents a protective group.

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