1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans,...

Details 1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans,... 1-(amino)indanes and (1,2-dihydro-3-amino)-benzofurans,...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/381 (2006.01) A61K 31/395 (2006.01) C07D 205/04 (2006.01) C07D 333/16 (2006.01) C07D 409/10 (2006.01) C07D 413/10 (2006.01) C07D 413/14 (2006.01)

Patent

CA 2509218

The present invention encompasses compounds of Formula (I): as well as the pharmaceutically acceptable salts and hydrates thereof. The compounds are useful for treating immune mediated diseases and conditions, such as bone marrow, organ and tissue transplant rejection. Pharmaceutical compositions and methods of use are included.

L'invention concerne des composés de la formule (I), ainsi que des sels pharmaceutiquement acceptables et des hydrates de ces derniers. Ces composés sont utiles dans le traitement de maladies et de conditions à médiation immune telles que la moelle osseuse, le rejet de transplantation d'organe et de tissus. L'invention porte aussi sur des compositions pharmaceutiques et des procédés d'utilisation associés.

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