1-(aminoalkoxyphenyl) derivatives of 2-oxohexahydro-indole

Details 1-(aminoalkoxyphenyl) derivatives of 2-oxohexahydro-indole 1-(aminoalkoxyphenyl) derivatives of 2-oxohexahydro-indole

C - Chemistry, Metallurgy

07

D

260/279, 260/306

C07D 403/12 (2006.01) C07D 209/32 (2006.01) C07D 209/34 (2006.01) C07D 295/10 (2006.01)

Patent

CA 1057753

ABSTRACT OF THE DISCLOSURE This invention relates to 1-aryl-2-oxo-2,4,5,6,7,7a- hexahydro-indoles, and acid addition salts thereof. In particular, the compounds have (.beta.-aminoethoxy- or ?-amino- propoxy)phenyl substituents, the amino groups in each case either being joined to two C1-5 alkyl groups or forming part of a heterocyclic group such as a pyrolidino, piperidino or morpholino group. Compounds in accordance with the invention have been found to exhibit interesting actions on the cardiovascular system in particular as vasodilators.

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