1-aminomethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline...

Details 1-aminomethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline... 1-aminomethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline...

C - Chemistry, Metallurgy

07

D

260/262, 260/277

C07D 401/12 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 235/30 (2006.01) C07D 239/42 (2006.01) C07D 257/06 (2006.01) C07D 285/135 (2006.01)

Patent

CA 1068276

ABSTRACT OF THE DISCLOSURE New 1,2.3,4-tetrahydroisoquinolines and their process of preparation are provided of the formula: Image wherein R is a substituted or unsubstituted hetorocyclic group and pharmaceutically acceptable salts thereof: the new compound have a relaxing activity on smooth muscles, especially on vas- cular-and visceral-smooth muscle; and can be used as vaso- dilator, intestinal-contraction inhibitor and bladder-contraction inhibitor.

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