1-aminomethyl-l-phenyl-cyclohexane derivatives as ddp-iv...

Details 1-aminomethyl-l-phenyl-cyclohexane derivatives as ddp-iv... 1-aminomethyl-l-phenyl-cyclohexane derivatives as ddp-iv...

A - Human Necessities

61

K

A61K 31/395 (2006.01) A61K 31/13 (2006.01)

Patent

CA 2673375

Compounds of the formula (I) are provided: wherein V, W, X, Y, Z, R3, R4, R5, R6, R7 and m are as defined in the specification; and pharmaceutically acceptable salts and prodrugs thereof. The compounds may be useful in the treatment or prevention of various diseases and conditions in which dipeptidylpeptidase-IV (DPP-IV) is implicated.

L'invention concerne des composés de formule (I) : dans laquelle V, W, X, Y, Z, R3, R4, R5, R6, R7 et m sont tels que définis dans la description; ainsi que leurs sels pharmaceutiquement acceptables et leurs promédicaments. Les composés peuvent être utiles pour le traitement ou la prévention de diverses maladies et troubles dans lesquels la dipeptidylpeptidase-IV (DPP-IV) est impliquée.

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