1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing...

Details 1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing... 1-aryl-3-aminoalkoxy pyrazoles as sigma ligands enhancing...

C - Chemistry, Metallurgy

07

D

C07D 231/22 (2006.01) A61K 31/4152 (2006.01) A61K 31/4155 (2006.01) A61K 31/485 (2006.01) A61P 29/00 (2006.01) C07D 231/26 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01)

Patent

CA 2722345

The invention relates to the use of a group of sigma receptor ligands of formula (I), for the potentiation of the analgesic effect of opioids and opiates and at the same time for decreasing the dependency induced by them.

L'invention porte sur l'utilisation d'un groupe de ligands des récepteurs sigma de formule (I), pour la potentialisation de l'effet analgésique d'opioïdes et d'opiacés et en même temps pour diminuer la dépendance induite par ceux-ci.

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