1-aryl-4-(aryloxycarbonyl)-piperazine derivatives for use as...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/75 (2006.01) A61K 31/496 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 213/74 (2006.01) C07D 213/76 (2006.01) C07D 213/80 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2526518

Novel piperazines of formula (I), pharmaceutical compositions comprising them and use thereof in the treatment and/or prevention of diseases and disorders related to hormone sensitive lipase. More particularly, the compounds are useful for the treatment and/or prevention of diseases and disorders in which modulation of lipolysis, such as decreased lipolysis is beneficial. (I).

L'invention concerne de nouvelles pipérazines de la formule (I), des composition pharmaceutiques les contenant ainsi que leurs utilisations dans le traitement et/ou la prévention de maladies et de troubles liés à la lipase hormonosensible. Plus particulièrement, les composés sont utiles dans le traitement et/ou la prévention de maladies et de troubles dans lesquels une modulation de la lipolyse, telle que la lypolise décrite, est bénéfique.

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