1-aryl-n-dialkylaminoalkyl-3,4-dihydro-2...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/12 (2006.01) C07D 215/08 (2006.01) C07D 217/02 (2006.01) C07D 217/06 (2006.01) C07D 217/14 (2006.01) C07D 217/16 (2006.01) C07D 217/18 (2006.01) C07D 217/20 (2006.01) C07D 317/52 (2006.01) C07D 317/58 (2006.01) C07D 319/18 (2006.01) C07D 401/12 (2006.01)

Patent

CA 1041501

Abstract of the Disclosure 1-Aryl-N-dialkylaminoalkyl-3,4-dihydro-2(1H)- isoquinolinecarboxamides and related N-substituted amides having anti-arrhythmic, anti-bacterial, anti-fungal, anti- algal and anthelmintic activity are described herein. The subject compounds can be prepared by reacting the appropriate 3,4-dihydro-2(1H)-isoquinolinecarbonyl chloride with a dialkylaminoalkylamine or similar compound, or by reacting an N-(chloroalkyl)-3,4-dihydro-2(1H)-isoquinoline- carboxamide with the appropriate dialkylamine or similar compound.

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