1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 or -4...

Details 1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 or -4... 1-aryl (o-alcoxyphenyl-4 piperazinyl-1)-2, -3 or -4...

C - Chemistry, Metallurgy

07

D

C07D 295/096 (2006.01) A61K 31/495 (2006.01) C07D 295/084 (2006.01)

Patent

CA 2139116

Use of compounds of general formula (I), in which R1, R2, R3, the same or different, are selected from a hydrogen atom, a hydroxy or methoxy group; R4 is selected form a hydrogen atom and an alkyl group having 1 to 5 carbon atoms; and n is an integer from 1 to 3. Said compounds are used in the preparation of a drug for the treatement of dysurias, especially related to a urethral hypertonia or benign prostate hypertrophia.

La présente invention concerne l'utilisation des composés de formule générale (1), dans laquelle R1, R2, R3 identiques ou différents, sont choisis parmi un atome d'hydrogène, un groupe hydroxy, un groupe méthoxy; R4 est choisi parmi un atome d'hydrogène et un groupe alkyle ayant de 1 à 5 atomes de carbone; et n est un nombre entier variant de 1 à 3; pour la prépa- ration d'un médicament utile pour le traitement des dysuries en particuier liées à une hypertonie urétrale ou à une hypertro- phie bénigne de la prostate.

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