C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/369.1, 260/3
C07D 303/38 (2006.01) C07D 303/22 (2006.01) C07D 303/24 (2006.01)
Patent
CA 1105041
Abstract of the disclosure: Compounds of the formula Image wherein R1 and R1' are the same or different and represent hydrogen, an alkyl or alkoxy radical having 1 - 4 carbon atoms, the allyl radical, halogen or the nitro group and R2 represents an acrylic acid radical or acrylic acid nitrile radical of the formulae Image or Image wherein R3 represents hydrogen, a (C1-C5)-alkyl radical, an unsubstituted aryl or aryl lower alkyl radical or an aryl or aryl- lower alkyl radical substituted by lower alkyl or lower alkoxy, R4 represents hydrogen or a (C1-C8)-alkyl radical, and R5 represents hydrogen, a lower alkyl or aryl- lower alkyl radical and process for their manufacture. The compounds according to the invention are valuable intermediate products for the production of 1-aryloxy-2-hydroxy-3-aminopropanes that are used as medicaments for the treatment of heart diseases.
279071
Fritsch Werner
Stache Ulrich
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Aktiengesellschaft
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