¬(1-arylpyrrolidin-2-yl)methyl| piperazine derivatives,...

Details ¬(1-arylpyrrolidin-2-yl)methyl| piperazine derivatives,... ¬(1-arylpyrrolidin-2-yl)methyl| piperazine derivatives,...

C - Chemistry, Metallurgy

07

D

C07D 403/06 (2006.01) A61K 31/495 (2006.01) C07D 207/09 (2006.01)

Patent

CA 2043981

[(1-ARYLPYRROLIDIN-2-YL)METHYL]PIPERAZINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS SYNTHELABO Descriptive abstract. [(1 Arylpyrrolidin-2-yl)methyl]piperazine derivatives corresponding to the formula Image (I) in which Z denotes a group of formula N-R1 in which R1 is either a hydrogen atom or a C1-3 alkyl group or a group of formula Ar-CnH2n in which n denotes 0, 1 or 2 and Ar denotes a phenyl group optionally substituted by one or more halogen atoms and/or C1-3 alkyl or C1-3 alkoxy radicals, or a group of formula COR2 in which R2 denotes the CH1, C8H5, CH2C6H5 or OC2H5 group and their salts of addition to pharmaceutically acceptable acids. Application in therapeutics.

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