1-azaxanthone-3-carboxylic acids and their production

Details 1-azaxanthone-3-carboxylic acids and their production 1-azaxanthone-3-carboxylic acids and their production

C - Chemistry, Metallurgy

07

D

260/276.2

C07D 491/052 (2006.01) C07D 491/04 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 1132984

1-Azaxanthone-3-carboxylic Acids and Their Production Abstract of the Disclosure Novel 1-azaxanthone-3-carboxylic acid derivatives, which are shown by the following formula (I) Image wherein R is hydrogen, alkyl, alkoxy or halogen; R1 and R2 are the same or different and each is hydrogen, alkyl or alkenyl; and m is 1 or 2; and their physiologically acceptable salts, are usable as effective medicines for preventing and/or treating allergic diseases. The compound of the formula (I) can be produced by reacting a compound of the formula: Image wherein R and m have the same meaning as defined above; R3 is carboxyl or group which is convertible into carboxyl through hydrolysis; X is alkyl phosphate radical or halogen, with a compound of the formula: Image wherein R1 and R2 have the same meaning as defined above, or its salt, and conducting hydrolysis, if necessary.

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