C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/553 (2006.01) A61K 31/675 (2006.01) C07F 9/568 (2006.01) C07F 9/6561 (2006.01)
Patent
CA 2073448
2073448 9110646 PCTABS00006 This invention relates to compounds having: (A) a bisphosphonic acid endgroup; (B) an azetidine- or hexamethylenimine-derived azacyclic endgroup; and (C) an alkyl and/or aryl group linking the bisphosphonic acid and azacyclic groups through the nitrogen atom of the azacyclic group. These compounds are useful as agents for regulating the metabolism of polyvalent ions, particularly calcium. This invention relates also to pharmaceutical compositions including said compounds and to methods of treating conditions for which said metabolism is involved by using said compounds.
Burns Christopher J.
Cheney Daniel L.
Youssefyeh Raymond D.
Burns Christopher J.
Cheney Daniel L.
Goudreau Gage Dubuc
Rhone-Poulenc Rorer International (holdings) Inc.
Youssefyeh Raymond D.
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