C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/14 (2006.01) A61K 31/495 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2222041
This invention relates to compounds of generic formula (I), to a process for preparation thereof, to a pharmaceutical composition comprising the same, and to a use of the same as a medicament. In formula (I), R1 is trihalo(lower)alkyl, R2 is trihalo(lower)alkyl, R3 is indolyl(lower)alkyl, -A- is -CH2- or (a), and -R4 is (b), (c) or (d) in which R5 is hydrogen or lower alkoxycarbonyl, R6 is hydrogen or lower alkanoyl, R7 is hydrogen, lower alkyl, lower alkanoyl, lower alkoxycarbonyl, lower alkoxy(lower)alkanoyl, cyclo(lower)alkylcarbonyl, aroyl or lower alkylsulfonyl, or its pharmaceutically acceptable salt.
La présente invention concerne des composés de formule générale (I), un procédé de préparation de ces derniers, une composition pharmaceutique comprenant ces derniers et l'utilisation de ces derniers comme médicament. Dans la formule (I), R1 est un trihalo-alkyle inférieur, R2 est un trihalo-alkyle inférieur, R3 est un indolyl-alkyle inférieur, -A- est -CH2- ou (a), et -R4 est (b), (c) ou (d) où R5 est un hydrogène ou un alcoxy inférieur-carbonyle, R6 est un hydrogène ou un alcanoyle inférieur, R7 est un hydrogène, un alkyle inférieur, un alcanoyle inférieur, un alcoxy inférieur-carbonyle, un alcoxy inférieur-alcanoyle inférieur, un cycloalkyl inférieur-carbonyle, un aroyle ou un alkyle inférieur-sulfonyle, ou un sel pharmaceutiquement acceptable de ces derniers.
Hagiwara Daijiro
Konishi Nobukiyo
Manabe Takashi
Matsuda Hiroshi
Matsuo Masaaki
Fujisawa Pharmaceutical Co. Ltd.
Ogilvy Renault
LandOfFree
1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivatives as... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivatives as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-benzoyl-2-(indolyl-3-alkyl)-piperazine derivatives as... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1832877