1.beta., 7, 8-trihydroxy vitamin d_ and 1.beta., 7,...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

260/352.1, 260/3

C07C 401/00 (2006.01) C07D 317/20 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1338832

There are disclosed novel compounds that can be used to derive therefrom a fragment that corresponds to an A- ring which is to be combined with fragments which respectively correspond to C- and D-rings in synthetic formation of vitamin D3 derivatives by cleaving the 7,8- bondings by means of oxidizing agents following any known process. According to the invention, there is provided an industrially efficient and effective method of manufacturing above compounds that utilizes chemical reaction of allylic acid to add an oxygen function group to position C(1), a method which is completely different from any existing synthetic methods.

592925

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