1-beta-d-arabinofuranosyl-(e)-5- (2-halogenovinyl) uracil...

Details 1-beta-d-arabinofuranosyl-(e)-5- (2-halogenovinyl) uracil... 1-beta-d-arabinofuranosyl-(e)-5- (2-halogenovinyl) uracil...

C - Chemistry, Metallurgy

07

H

C07H 19/09 (2006.01) A61K 31/70 (2006.01) C07H 19/06 (2006.01)

Patent

CA 2085994

ABSTRACT The present invention relates to a novel 1-.beta.-D- arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivative represented by the following formula (I), whose concentration in blood as XVAU can be kept high for many hours when it is administered orally. The present invention also relates to an antiviral agent comprising as an active ingredient the compound of the present invention. Further, the present invention relates to a method for treating viral diseases which comprises administering to a patient with a viral disease a safe and effective amount of the compound of the present invention. Image (I) wherein X represents a halogen; and R1, R2 and R3, which may be the same or different, each represent a hydrogen atom, a lower alkyl group or an aralkyl group, provided that R1, R2 and R3 are not hydrogen at the same time.

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