1-.beta.-methyl-2-thiolic carbapenem derivatives

Details 1-.beta.-methyl-2-thiolic carbapenem derivatives 1-.beta.-methyl-2-thiolic carbapenem derivatives

C - Chemistry, Metallurgy

07

D

C07D 477/00 (2006.01) C07D 477/20 (2006.01)

Patent

CA 2102003

ABSTRACT The present invention relates to new 1- .beta. -methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and producing method thereof. (I) Image The above-mentioned compound is very stable against DHP-1 enzyme due to effective shielding of carbapenem ring structually and is highly effective in both gram-positive and gram-negative microorganism, especially has a remarkable effect on the Pseudomonas aeruginosa known as a disease germ having strong resistance.

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