1-carba (dethia) cephalosporin 3-triflate ester antibiotics

Details 1-carba (dethia) cephalosporin 3-triflate ester antibiotics 1-carba (dethia) cephalosporin 3-triflate ester antibiotics

C - Chemistry, Metallurgy

07

D

167/187, 260/255

C07D 471/04 (2006.01) A61K 31/33 (2006.01) A61K 31/455 (2006.01) C07D 463/00 (2006.01)

Patent

CA 1262356

ABSTRACT 7.beta.-Acylamino-3-trifluoromethylsulfonyloxy-1- carba 3-cephem-4-carboxylic acid antibiotic compounds, esters and salts thereof, and the corresponding 7-amino and protected 7-amino 1-carbacephalosporins are provided. The 3-trifluoromethylsulfonyloxy-substituted 1-carba- cephalosporins also are useful in a process for prepar- ing 3-halo-1-carbacephalosporins which comprises dis- placing the 3-trifluoromethylsulfonyloxy ester group with halide ion in an aprotic polar solvent. These antibiotic compounds are useful in the treatment of infectious diseases in man and animals and the 1- carbacephalosporin compounds particularly have enhanced potency against infectious and resistant microorganisms.

513962

Affiliated with

Also associated with

Rating

1-carba (dethia) cephalosporin 3-triflate ester antibiotics does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-carba (dethia) cephalosporin 3-triflate ester antibiotics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-carba (dethia) cephalosporin 3-triflate ester antibiotics will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1270500