1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(oxo-...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) C07D 215/56 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 1218069

ABSTRACT OF THE DISCLOSURE The invention relates to 1-cyclopropyl-6-fluoro-1,4- dihydro-4-oxo-7-[4-(oxo-alkyl)-1-piperazinyl]-quinoline-3- carboxylic acids of Formula (I) Image (I) in which R1 denotes hydrogen, straight-chain or branched alkyl having 1 to 4 carbon atoms and phenyl which is optionally substituted 1-3 times by trifluoromethyl, methyl, ethyl, fluorine, chlorine, bromine, phenyl, hydroxyl or alkoxy having 1-4 carbon atoms, R2, R3, R4 and R5 can be identical or different and denote hydrogen, methyl, ethyl, n- or i-propyl, X denotes O, N-O-R', N-NH-R'' and (OR''')2, in which R' represents hydrogen, straight- chain or branched alkyl having 1 to 6 carbon atoms, cycloalkyl having 5 to 6 carbon atoms, chlorobenzyl or tetrahydropyranyl, R'' represents methyl, phenyl, carbamoyl or thiocarbamoyl and R''' represents methyl and ethyl or (OR''')2 represents Image and A denotes a straight chain alkylene group having 1-4 carbon atoms, which is optionally substituted by alkyl having 1-4 carbon atoms or phenyl, processes for their manufacture, compositions containing them and use of said compounds and compositions as antibacertial and/or feedstuff additives.

444207

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