1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix...

Details 1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix... 1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix...

C - Chemistry, Metallurgy

07

D

C07D 239/96 (2006.01) A61K 31/517 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2433960

The aim of the invention is the discovery and investigation of novel chemical entities of a non-proteinogenic structure which have a matrix- metalloproteinase(MMP)-inhibiting effect. Said aim is achieved by means of the synthesis of dimercaptoalkyl-substituted quinazolin-2,4(1H,3H)-diones. Compounds of the above substance class display an unexpectedly clear and hence pharmacologically interesting MMP-inhibiting effect.

L'invention a pour objet la mise au point et l'analyse de nouvelles substances chimiques à structure non protéinogène qui ont une action d'inhibition sur la métalloprotéinase matricielle (MMP), grâce à la synthèse de chinazoline-2,4(1H,3H)-diones substituées par dimercaptoalkyle. Des composés de ce type ont de manière surprenante une nette action d'inhibition de MMP qui s'avère intéressante d'un point de vue pharmacologique.

Affiliated with

Also associated with

Rating

1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-dimercaptoalkylquinazolin-2,4(1h,3h)-diones as matrix... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1954041