1-(h-1,2,4-triazol-1-yl)butan-2-ol derivatives

Details 1-(h-1,2,4-triazol-1-yl)butan-2-ol derivatives 1-(h-1,2,4-triazol-1-yl)butan-2-ol derivatives

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2405919

The present invention is directed to new 1-(1H-1,2,4-triazol-1-yl)butan-2-ol derivatives of the formula (I), and pharmaceutically acceptable salts thereof wherein Q, R, X, Y and Z are the same as defined in the claims and the description. 1-(1H-1,2,4-triazol-1-yl)butan-2-ol derivatives of the present invention have antifungal activity and are useful for the treatment of fungal diseases.

L'invention concerne des dérivés 1-(1H-1,2,4-triazol-1-yl)butan-2-ol de formule (I), ainsi que leurs sels acceptables sur le plan pharmaceutique, dans laquelle Q, R, X, Y et Z sont identiques comme définis dans les revendications et dans la description. Les dérivés 1-1H-1,2,4-triazol-1-yl)butan-2-ol de l'invention possèdent une activité antifongique et sont utiles pour le traitement de maladies fongiques.

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