1'-hydroxy-5-lower alkoxy-2-lower alkyl-7,8-cyclopentano...

C - Chemistry – Metallurgy – 07 – D

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260/281.7

C07D 221/16 (2006.01)

Patent

CA 1074320

Abstract of the Disclosure Novel tetrahydroisoquinolines and their method of preparation by chemically reducing a 5-lower alkoxy-2-lower alkyl-7,8-cyclopentano[h]- 1,2,3,4-tetrahydroisoquinoline-1'-one to a 1'-hydroxy-5-lower alkoxy-2-lower alkyl-7,8-cyclopentano[h]-1,2,3,4-tetrahydroisoquinoline. The compounds are useful, primarily as intermediates, for the formation of other tetrahydro- isoquinolines used to effect pharmacological activity in animals.

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