1-hydroxy-5-oxo-5h-pyrido¬3,2-a|phenoxazine -3-carboxylic...

C - Chemistry – Metallurgy – 07 – D

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C07D 513/04 (2006.01) A61K 31/535 (2006.01) C07D 498/04 (2006.01)

Patent

CA 1311477

1-HYDROXY-5-OXO-5H-PYRIDO[3,2-a]PHENOXAZINE-3-CARBOXYLIC ACID ESTERS Abstract: The present invention is directed to compounds represented by the general formula Image wherein R is an alkyl group having 1 - 10 carbon atoms. Since they have excellent affinities for tissues with particular high corneal permeability and show anticataract activity at low concentrations, the compounds are of value as prophylactic and therapeutic agents for cataract treatment.

541474

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