1-(hydroxylaminoalkyl) indole derivatives as inhibitors of...

Details 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of... 1-(hydroxylaminoalkyl) indole derivatives as inhibitors of...

C - Chemistry, Metallurgy

07

D

C07D 209/04 (2006.01) C07D 209/08 (2006.01) C07D 209/30 (2006.01) C07D 401/02 (2006.01) C07D 403/02 (2006.01) C07D 413/02 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2063956

137/GL51 18288 TITLE OF THE INVENTION 1-(HYDROXYLAMINOALKYL)INDOLE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS ABSTRACT Compounds having the formula I: Image I are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-aller- gic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemiz, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.

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