1-n-(.omega.-amino-.alpha.-hydroxyalkanoyl)-2',3'-dideoxy-...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/234 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1212941

1-N-(.omega.-amino-.alpha.-hydroxyalkanoyl)-2',3'-dideoxy- kanamycin A and the production of the same ABSTRACT OF THE DISCLOSURE 1-N-(L-3-amino-2-hydroxypropionyl)-2',3'-dideoxy- kanamycin A and 1-N-(L--amino-2-hydroxybutyryl)-2',3'- dideoxykanamycin A are now provided which each is a new compound useful as antibacterial agent. The new compounds each is produced by acylating the 1-amino group of 2',3'- dideoxykanamycin A with L-3-amino-2-hydroxypropionic or L-4-amino-2-hydroxybutyric acid.

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