1-oxo-1-dethia-cephalosporin compounds and antibacterial...

Details 1-oxo-1-dethia-cephalosporin compounds and antibacterial... 1-oxo-1-dethia-cephalosporin compounds and antibacterial...

C - Chemistry, Metallurgy

07

D

167/187, 260/244

C07D 498/04 (2006.01) A61K 31/535 (2006.01) C07D 505/00 (2006.01)

Patent

CA 1268177

00032 TITLE OF THE INVENTION NEW 1-OXA-1-DETHIA-CEPHALOSPORIN COMPOUNDS AND ANTIBACTERIAL AGENT COMPRISING THE SAME. ABSTRACT OF THE INVENTION The subject invention includes a 1-oxa-1- dethia-cephalosporin compound respresented by the general formula (1) Image (I) 2764P/0970A - 2 - 00032 wherein R1 is a group of the formula: Image where R5 is a methyl group, an ethyl group, a carboxymethyl group or a 2-carboxy isopropyl group, or R1 is a group of the formula: Image where R6 is a hydrogen atom, a 4-ethyl-2,3- dioxopiperazine-1-yl group, a 3,4-dihydroxy phenyl group or a 5- and 6-membered heterocyclic radical having 2 ring nitrogens as the sole hetero substituent in the ring and having at least one hetero group on the carbon adjacent to the ring nitrogens.

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