(1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or...

Details (1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or... (1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or...

C - Chemistry, Metallurgy

07

C

260/507.1, 260/3

C07C 59/76 (2006.01) A61K 31/495 (2006.01) A61K 31/585 (2006.01) C07C 45/46 (2006.01) C07C 45/63 (2006.01) C07C 45/65 (2006.01) C07C 45/67 (2006.01) C07C 45/68 (2006.01) C07C 45/71 (2006.01) C07C 49/747 (2006.01) C07C 49/755 (2006.01) C07C 49/84 (2006.01) C07C 51/487 (2006.01) C07C 59/90 (2006.01) C07C 205/45 (2006.01) C07C 255/13 (2006.01) C07C 333/18 (2006.01) C07D 241/26 (2006.01) C07D 257/04 (2006.01) C07D 333/14 (2006.01) C07D 333/18 (2006.01) C07D 333/22 (2006.01) C07D 409/12 (2006.01) C07D 475/08 (20

Patent

CA 1063125

ABSTRACT OF THE DISCLOSURE (1-Oxo-2-aryl or thienyl-2-substituted-5- indanyloxy (or thio)] alkanoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. Also disclosed are processes for the preparation of such [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)] alkanoic acids, pharmaceutical compositions comprising therapeutically effective amounts of such compounds and methods of treat- ment comprising administering such compounds and composi- tions.

210670

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