1-phenethylpiperidine derivatives and their use as opioid...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/32 (2006.01) A61K 31/445 (2006.01) A61K 31/4525 (2006.01) A61P 25/00 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2641913

This invention relates to novel 1-phenethylpiperidine derivatives of formuia (I) useful as opioid receptor ligands. More specifically, the invention provides compounds useful as µ opioid receptor ligands. In other aspects the invention relates to the use of these compounds in a method for therapy, such as for the treatment of pain, and to pharmaceutical compositions comprising the compounds of the invention.

Cette invention concerne des nouveaux dérivés de 1-phénétylpipéridine représentés par la formule (I), convenant comme ligands de récepteurs opioïdes. Plus précisément, l'invention porte sur des composés utiles en tant de ligands de récepteurs opioïdes de type µ. Selon d'autres aspects, l'invention concerne l'utilisation de ces composés dans le cadre d'une méthode thérapeutique ainsi que des compositions contenant les composés de l'invention.

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