1-phenyl 1-thio-d-glucitol derivative

Details 1-phenyl 1-thio-d-glucitol derivative 1-phenyl 1-thio-d-glucitol derivative

C - Chemistry, Metallurgy

07

D

C07D 335/02 (2006.01) A61K 31/382 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/08 (2006.01) A61P 3/10 (2006.01) A61P 7/10 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01) A61P 19/06 (2006.01) A61P 25/00 (2006.01) A61P 27/02 (2006.01) A61P 31/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2672176

Disclosed is a 1-phenyl 1-thio-D-glucitol compound having the formula (I) or the like, a pharmaceutically acceptable salt thereof, a hydrate of the compound or the pharmaceutically acceptable salt, or a pharmaceutical agent comprising the compound, the pharmaceutically acceptable salt or the hydrate as an active ingredient, which can inhibit both the activities of SGLT1 and SGLT2 and has both of an effect of inhibiting the absorption of glucose through a digestive tract and an urinary glucose excretion effect, and therefore is useful as a new type of prophylactic or therapeutic agent for diabetes, a diabetes-related disease or a diabetic complication.

L'invention concerne un composé de 1-phényl 1-thio-D-glucitol représenté par la formule (I) ou similaire, un sel pharmaceutiquement acceptable de celui-ci, un hydrate du composé ou du sel pharmaceutiquement acceptable, ou un agent pharmaceutique comprenant le composé, le sel acceptable pharmaceutiquement ou l'hydrate en tant que principe actif, qui peuvent inhiber à la fois les activités de SGLT1 et SGLT2 et ont à la fois un effet d'inhibition de l'absorption de glucose à travers le système digestif et un effet d'excrétion urinaire de glucose, et sont donc utiles en tant que nouveau type d'agent prophylactique ou thérapeutique pour le diabète, une maladie liée au diabète ou une complication diabétique.

Affiliated with

Also associated with

Rating

1-phenyl 1-thio-d-glucitol derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-phenyl 1-thio-d-glucitol derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-phenyl 1-thio-d-glucitol derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1928915