1-phenyl-2(1h,3h)-indolone psycho-therapeutic agents

Details 1-phenyl-2(1h,3h)-indolone psycho-therapeutic agents 1-phenyl-2(1h,3h)-indolone psycho-therapeutic agents

C - Chemistry, Metallurgy

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C07D 209/34 (2006.01) C07C 43/225 (2006.01) C07D 209/08 (2006.01) C07D 209/38 (2006.01) C07D 401/02 (2006.01) C07D 403/02 (2006.01)

Patent

CA 1194871

Abstract Certain substituted 1-phenyl-3- (aminoalkylidene)- 2(1H3H)-indolones are highly potent gabaergic agents, valuable in the treatment of individuals suffering from schizophrenia or reversing the side effects of a pre- viously or concurrently administered neuroleptic agent; or in the treatment of epilepsy. A wider class of substituted 1-phenyl-3-(aminoalkylidene)- 2(1H,3H)-indolones, together with 1-phenyl-3-(2- pyrrolidinylidene)-2(1H,3H)-indolones, and homologs thereof, are valuable in the treatment of anxiety.

436845

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