1-phenylalkyl-3-phenylurea derivatives

C - Chemistry – Metallurgy – 07 – C

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C07C 275/30 (2006.01) A61K 31/17 (2006.01) C07C 273/18 (2006.01) C07C 275/28 (2006.01)

Patent

CA 2022346

Abstract: Novel 1-phenylalkyl-3-phenylurea derivatives represented by the following formula (I): Image (I) wherein R1 is an alkyl group of 1 to 8 carbon atoms, an alkoxy group of 1 to 5 carbon atoms or a halogen atom, R2 is an alkyl group of 1 to 15 carbon atoms, each of R3 and R4 is independently an alkyl group of 1 to 5 carbon atoms, m is an integer of 1 to 3, and n is 0 or 1, are provided. The compounds are potent in reducing the cholesterol level in serum, and useful for treating hyperlipemia and atherosclerosis.

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