1-phenylpyrazole compounds and medicinal application thereof

Details 1-phenylpyrazole compounds and medicinal application thereof 1-phenylpyrazole compounds and medicinal application thereof

C - Chemistry, Metallurgy

07

D

C07D 231/14 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2269721

1-Phenylpyrazole compounds represented by general formula (1) such as 5-amino- 1-(3-cyano-4-isobutoxyphenyl)pyrazole-4-carboxylic acid, optical isomers thereof, and medicinally acceptable salts thereof. These compounds have a xanthine oxidase inhibitory effect and are useful as remedies for diseases such as hyperuricemia and gout.

L'invention concerne des composés de 1-phénylpyrazole représentés par la formule générale (1), par ex. acide 5-amino-1-(3-cyano-4-isobutoxyphényl)pyrazole-4-carboxylique, leurs isomères optiques et leurs sels pharmaceutiquement acceptables. Ces composés ont un effet inhibiteur sur la xanthine oxydase et s'utilisent comme médicaments pour des maladies telles que l'hyperuricémie et la goutte.

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