C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/279.25, 260/
C07D 491/107 (2006.01) C07D 307/94 (2006.01) C07D 491/10 (2006.01) C07D 495/10 (2006.01) C07D 495/20 (2006.01)
Patent
CA 1169863
ABSTRACT OF THE DISCLOSURE Derivatives of formula : Image in which Z?represents : - either an amino group of structure ?N-R1 where R1 repre- sents a linear or branched alkyl group with 1 to 5 carbon atoms or a phenyl group possibly substituted by a chlorine atom, in which case : . n = 1 or 2, . the pair Image assumes the following values : (S, C=O), (S, CH2), (O, CH2), (O, CH-C6H5), and . R represents a hydrogen or halogen atom, one or more methoxy groups or the butadiene-1,3 ylene chain Image fixed in position 5,6 of the phenyl nucleus and thus forming with this latter a naphtyl nucleus ; - or a methylene group (-CH2-), in which case ; . n = 1 or 2, . A represents the oxygen atom, . Image represents a carbonyl group (?C=O) or thiocarbonyl group (?C=S), and . R has the same meanings as previously, as well as the mineral or organic acid additions salts thereof. These compounds are useful as medicaments.
394968
Bucher Bernard
Dostert Philippe
Lacour Alain
Langlois Michel
Moinet Gerard
Delalande S.a.
Fetherstonhaugh & Co.
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