C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/298.5
C07D 491/044 (2006.01) C07D 207/20 (2006.01) C07D 491/04 (2006.01)
Patent
CA 1135701
ABSTRACT OF THE INVENTION 3,4-Epoxypyrrolidines substituted in the 1-position with alkyl, cycloalkyl and phenylalkyl are disclosed which have pharmaceutical application in cataract prevention in animals and as intermediates in preparation of trans-3- aryloxy-4-hydroxypyrrolidines. The epoxypyrrolidines are prepared by a novel route involving chlorination of pyrrolines in aqueous medium.
343329
Walsh David A.
Welstead William J. Jr.
Robins (a. H.) Company Inc.
Smart & Biggar
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