1-(substituted-aryl)-dihydro-1h-pyrrolizine 3,5¬2h,...

Details 1-(substituted-aryl)-dihydro-1h-pyrrolizine 3,5¬2h,... 1-(substituted-aryl)-dihydro-1h-pyrrolizine 3,5¬2h,...

C - Chemistry, Metallurgy

07

D

167/233, 260/299

C07D 487/04 (2006.01) A61K 31/40 (2006.01) C07C 205/53 (2006.01) C07D 207/26 (2006.01)

Patent

CA 1252105

ABSTRACT l-(Substituted-aryl)-dihydro-lH-pyrrolizine-3,5- [2H,6H]-diones are effective cognition activating agents for the treatment of senility and for reversing amnesia. Pharmaceutical compositions containing these compounds and a method of treating senility or of reversing amnesia are also disclosed. The novel compounds have the general formula: Image wherein X and Y are independently hydrogen, alkyl of from one to six carbon atoms, alkoxy of from one to six carbon atoms, chloro- or trifluoromethyl. .

479812

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