1-¬(substituted-naphthyl)ethyl|imidazole derivatives

Details 1-¬(substituted-naphthyl)ethyl|imidazole derivatives 1-¬(substituted-naphthyl)ethyl|imidazole derivatives

C - Chemistry, Metallurgy

07

D

260/305, 260/315

C07D 405/06 (2006.01) C07C 45/46 (2006.01) C07C 45/63 (2006.01) C07D 233/60 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1153000

Abstract of the Disclosure Compounds of the formula Image (I) wherein m is the integer 1, 2 or 3; R is independently selected from the group C1 to C6 alkyl, C1 to C6 alkoxy, halo, trifluoromethyl and hydroxy when m is the integer 1, 2 or 3 and methylenedioxy when m is the integer 2; Z is hydroxymethylene, esterified hydroxymethylene, alkoxymethylene, alkylthiomethylene, carbonyl, or ketal-, thioketal- or hemithioketal-protected carbonyl, and the pharmaceutically acceptable acid addition salts thereof, are useful as anticonvulsants, anti-secretory agents and spermatocides.

346988

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