1-(substituted phenylthiocarbamyl) 3,3-disubstituted...

Details 1-(substituted phenylthiocarbamyl) 3,3-disubstituted... 1-(substituted phenylthiocarbamyl) 3,3-disubstituted...

C - Chemistry, Metallurgy

07

D

260/544.3

C07D 295/195 (2006.01) C07C 335/16 (2006.01)

Patent

CA 1177850

PR-5665A 1-(SUBSTITUTED PHENYLTHIOCARBAMYL)3,3-DISUBSTITUTED FORMAMIDINES AND THEIR USE AS PHARMACEUTICAL AGENTS Abstract of the Invention 1-(substituted phenylthiocarbamyl) 3,3-disubstituted formamidine compounds having the structural formula Image wherein n is 1, 2 or 3, R is alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, alkylthio having 1 to 4 carbon atoms, halogen, nitro, acyl having 1 to 4 carbon atoms, hydroxyl and Image wherein R3 and R4 have the same meaning as R1 and R2 defined below, R1 and R2 are the same or different and are alkyl having 1 to 6 carbon atoms, or taken together represent the chain -(CH2)p-(X)m-(CH2)q and forming a ring structure with the nitrogen to which they are bound wherein p is 1, 2 or 3, q is 2 or 3, X represents -O-, -S-, -SO-, -SO2-, -NR3-, R3 is hydrogen or alkyl having 1 to 6 carbon atoms, and m is 0 or 1 and their use as pharmaceutical agents.

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