1-sulfonylindole derivatives, their preparation and their...

A - Human Necessities – 61 – K

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Details

A61K 31/404 (2006.01) A61P 3/04 (2006.01) A61P 25/00 (2006.01) C07D 209/40 (2006.01) C07D 401/04 (2006.01)

Patent

CA 2533996

The present invention refers to new sulfonamide derivatives, of general formula (la, lb, 1c), (I) ,(1 a, I b, I c), optionally in form of one of their stereoisomers, preferably enantiomers or diastereomers, their racemate, or in form of a mixture of at least two of their stereoisomers, preferably enantiomers or diastereomers, in any mixing ratio, or their salts, preferably their corresponding physiologically acceptable salts or corresponding solvates; to the processes for their preparation, to their application as medicaments in human and/or veterinary therapeutics, and to the pharmaceutical compositions containing them. The new compounds of the present invention can be used in the pharmaceutical industry as intermediates and for preparing medicaments.

La présente invention a trait à de nouveaux dérivés de sulfonamide, de formule générale (la, lb, 1c), (I), éventuellement sous la forme d'un de leurs stéréoisomères, de préférence d'énantiomères ou de diastéréomères, leur mélange racémique, ou sous la forme d'un mélange d'au moins deux de leurs stéréoisomères, de préférence d'énantiomères ou diastéréomères, dans un quelconque rapport de mélange, ou leurs sels, de préférence leurs sels ou leurs solvates correspondants physiologiquement acceptables ; à leurs procédés de préparation, à leur utilisation comme médicaments dans la thérapeutique humaine et/ou vétérinaire, et aux compositions pharmaceutiques les contenant. Les nouveaux composés de la présente invention peuvent être utilisés dans l'industrie pharmaceutique en tant qu'intermédiaires et pour la préparation de médicaments.

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