1-thiogalactose derivatives

Details 1-thiogalactose derivatives 1-thiogalactose derivatives

C - Chemistry, Metallurgy

07

H

C07H 15/20 (2006.01) A61K 31/70 (2006.01) C07H 5/10 (2006.01) C07H 15/14 (2006.01) C07H 15/18 (2006.01) C07H 15/203 (2006.01) C07H 15/22 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2256016

Disclosed are novel 1-thiogalactose derivatives which inhibit binding of toxins, such as heat-labile enterotoxin or cholera toxin, to their receptors either in vitro or in vivo. Additionally, disclosed are compounds which inhibit binding of organisms (e.g., bacteria, virus, fungi, and the like), such as Vibrio cholerae and enterotoxigenic strains of Escherichia coli, to their cell surface receptors.

L'invention a trait à de nouveaux dérivés de 1-thio-galactose inhibant la fixation de toxines, d'une entérotoxine thermolabile ou d'une toxine cholérique, notamment, à leurs récepteurs que ce soit in vitro ou in vivo. Cette invention concerne, de surcroît, des composés inhibant la fixation d'organismes (par exemple, des bactéries, des virus, des champignons et analogue), tels que le Vibrio cholerae et des souches entérotoxigènes d'Escherichia coli, à leurs récepteurs de surface cellulaire.

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