10(1-hydroxyethly)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-...

Details 10(1-hydroxyethly)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-... 10(1-hydroxyethly)-11-oxo-1-azatricyclo[7.2.0.0.3.8]undec-2-...

C - Chemistry, Metallurgy

07

D

C07D 477/00 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2067741

Compounds of general formula (I) in which R1 represents the group (a), where R4 represents a hydrogen atom or a C1-4 alkyl group; p is 0 or 1; R5 is a group selected from C1-6 alkyl, C5-8 cycloalkyl optionally substituted by a C1-3 alkyl group, phenyl and C1-4 alkyl substituted by a C1-3 alkoxy group; and R2 is a group OR3 where R3 is a C1-5 alkyl group, are orally administrable and exhibit broad spectrum antibacterial activity.

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