10a1 retroviral packaging cells and uses thereof

Details 10a1 retroviral packaging cells and uses thereof 10a1 retroviral packaging cells and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) C12N 15/86 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2244663

Retroviral packaging cells produce replication-defective retroviral vector particles capable of binding to Glvr-1 or Ram-1 retroviral receptors on target cells and are useful in gene therapy. The packaging cell employs a vector encoding a 10A1 retroviral env protein and produces the retroviral particles at high titer.

Cette invention concerne des cellules d'encapsidation de vecteurs rétroviraux qui produisent des particules de vecteurs rétroviraux, défectueux vis à vis de la réplication, capables de se lier à des récepteurs rétroviraux du type Glvr-1 ou Ram-1 sur des cellules cibles et qui sont utiles en thérapie génique. Ladite cellule d'encapsidation utilise un vecteur codant une protéine enveloppe d'un vecteur rétroviral de classe 10A1 et elle produit un titrage élevé de particules rétrovirales.

Affiliated with

Also associated with

Rating

10a1 retroviral packaging cells and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 10a1 retroviral packaging cells and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 10a1 retroviral packaging cells and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1903706