C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
167/193, 260/21,
C07J 41/00 (2006.01) A61K 31/56 (2006.01) C07J 1/00 (2006.01) C07J 21/00 (2006.01) C07J 71/00 (2006.01)
Patent
CA 1297472
ABSTRACT The present invention is concerned with 11-aryl- oestrane and 11-arylpregnane derivatives, characterized in that these derivatives have the following structure: Image wherein R1 is an aryl group with an Image group as substituent, X and Y each being separately H or a (1- 4C) hydro- carbon radical or together a (2-6 C) hydrocarbon radical; R2 is an alkyl group containing 1-4 carbon atoms; R3 is H, OH, a saturated or unsaturated hydrocarbon radical containing 1-8 carbon atoms, at least provi- ded with a hydroxyl, oxo, halogen, azido or nitrile group; an acyloxy or an alkoxy group; R4 is a hydroxyl, an acyloxy or an alkoxy group or an acyl group optionally provided with a hydroxyl, alkoxy, acyloxy or halogen group; or R3 and R4 together form a ring system; and R5 is a hydrocarbon group containing 1-4 carbon atoms, and further with processes for the preparation of these compounds and with pharmaceutical preparations comprising these compounds. The compounds according to the present invention exhibit antiprogestin activity.
564606
de Jongh Hendrik Paul
Groen Marinus Bernard
Akzo N.v.
Fetherstonhaugh & Co.
LandOfFree
11-aryloestrane and 11-arylpregnane derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 11-aryloestrane and 11-arylpregnane derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 11-aryloestrane and 11-arylpregnane derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1229082