11 .beta.-(4-isoprepenylphenyl)estra-4,9-dienes, their...

Details 11 .beta.-(4-isoprepenylphenyl)estra-4,9-dienes, their... 11 .beta.-(4-isoprepenylphenyl)estra-4,9-dienes, their...

C - Chemistry, Metallurgy

07

J

167/191, 260/38,

C07J 1/00 (2006.01) C07J 17/00 (2006.01) C07J 21/00 (2006.01) C07J 41/00 (2006.01)

Patent

CA 1289944

Abstract of the Disclosure 11 .beta.-(4-isopropenylphenyl)-estra-4,9-dienes of general Formula I Image (I) wherein X is an oxygen atom or a hydroxyimino grouping N ? OH, R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom or an acyl residue of 1-10 carbon atoms, R3 is a hydrogen atom, the cyanomethyl group, -(CH2)n-, CH2Z, -CH=CH-(CH2)mZ or -C?C-Y wherein n = 0 to 5 and m = 1 to 4, Z meaning a hydrogen atom or the OR4 group with R4 meaning a hydrogen atom, an alkyl or alXanoyl group each of 1-4 carbon atoms, and Y meaning a hydrogen, chlorine, fluorine, iodine or bromine atom, an alkyl, hydroxyalkyl, alkoxyalkyl or acyloxyalkyl group each of 1-4 carbon atoms in the alkyl or acyl residue, possess antiprogestational activity.

542897

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