11.beta.-alkyl steroids of the estrane series

C - Chemistry – Metallurgy – 07 – J

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260/55

C07J 11/00 (2006.01)

Patent

CA 1038373

Title: Novel 11.beta.-alkyl-steroids of the estrane series. Abstract of the Disclosure The present invention relates to novel steroids of the estrane series having the general formula I: I Image , wherein R1 and R2 = an alkyl group having 1-4 carbon atoms, R3 = oxygen or (.alpha.P)(.beta.Q), wherein P = hydrogen or a saturated or an unsaturated alkyl group having 1-4 carbon atoms, and Q = a free, esterified or etherified hydroxyl group, and a double bond is present departing from carbon atom 5, and to the preparation thereof. The compounds according to the invention possess very valuable anabolic, androgenic, estrogenic, anti-estrogenic, progestative, anti-progestative, ovulation-inhibiting and gonad-inhibiting properties and are furthermore of value owing to their peripheral anti-fertility activity.

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